How can we patch a module globally in a project?

How can we patch a module globally in a project?

References

Reference NO 1

http://stackoverflow.com/questions/15193684/how-can-we-patch-a-module-globally-in-a-project

Reference NO 2

http://washort.twistedmatrix.com/2011/01/modules-in-python-good-bad-and-ugly.html

Reference NO 3

https://drupal.org/node/251466

Reference NO 4

http://www.voidspace.org.uk/python/mock/

Reference NO 5

https://pypi.python.org/pypi/unittest2

Reference NO 6

http://django-configurations.readthedocs.org/

Reference NO 7

http://code.google.com/p/modwsgi/wiki/ApplicationIssues

Reference NO 8

http://wiki.alfresco.com/wiki/Developing_an_Alfresco_Module